CV

In Revision

• Overbey, Eliah G., Braden T. Tierney, JangKeun Kim, Kirill Grigorev, Jiwoon Park, Nadia Houerbi, Sebastian Garcia Medina “The space omics and medical atlas (SOMA): A comprehensive data resource and biobank for astronauts.” Nature.

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• Jones, Christopher, Eliah G. Overbey, Jacob Lacombe, A.J. Ecker, Cem Meydan, Krista Ryon, Braden Tierney, et al. “The SpaceX Inspiration4 Mission: in-flight biomedical research, multi-omics, cognitive, and physiological metrics from the first all-civilian orbital spaceflight.” Nature.

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• Kim, JangKeun, Braden T. Tierney, Eliah G. Overbey,  Ezequiel Dantas, Jiwoon Park, S. Anand Narayanan, Fei Wu, et al. “Single-cell multiome and immune profiles of the Inspiration4 crew reveal cell-type, sex, and  microbiome-specific responses to spaceflight.” Nature Communications.

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• Mason, Christopher E., James Green, Konstantinos I. Adamopoulos, Evan E. Afshin, Jordan J. Baechle, Mathias Basner, Susan M. Bailey, Josef Borg, Joseph Borg, Jared T. Broddrick, Marissa Burke, Andrés Caicedo, Verónica Castañeda, Subhamoy Chatterjee, George Church, Sylvain V. Costes, Rajeev I. Desai, Raja Dhir, Juan Esteban Diaz, Sofia M. Etlin, David Furman, J. Sebastian Garcia-Medina, Stefania Giacomello, Anjali Gupta, Amira Hassanin, Nadia Houerbi, Iris Irby, Peter Jirak, Christopher W. Jones, Khaled Y. Kamal, Brian D. Kangas, Fathi Karouia, JangKeun Kim, Joo Hyun Kim, Ashley Kleinman, John M. Lawler, Jessica A. Lee, Charles L. Limoli, Matthew MacKay, J. Tyson McDonald, Cem Meydan, Jakub Mieczkowski, Masafumi Muratani, Deena Najjar, Mariam A. Othman, Eliah G. Overbey, et al. “The Second Space Age: Omics, Platforms, and Medicine Across Orbits”. Nature.

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• Grigorev, Kirill, Theodore M. Nelson, Eliah G. Overbey, Nadia Houerbi, JangKeun Kim, Deena Najjar, Namita Damle, et al. “Direct RNA sequencing of astronaut blood reveals spaceflight-associated m6A increases and hematopoietic transcriptional responses”. Nature Communications.

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• Rutter, Lindsay A., Matthew J. MacKay, Henry Cope, Nathaniel J. Szewczyk, JangKeun Kim, Eliah G. Overbey, Braden T. Tierney, et al. “Protective alleles and precision healthcare in crewed spaceflight.” Nature Communications.

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• Al-Turki, Taghreed M.,  David G. Maranon, Christopher B. Nelson, Aidan M. Lewis, Jared J. Luxton, Lynn E. Taylor, Noelia Altina, Fei Wu, JangKeun Kim, Namita Damle, Eliah G. Overbey, et al. “Telomeric RNA (TERRA) mediates telomeric DNA damage response to spaceflight and radiation exposure”. NPJ Microgravity.

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• Houerbi, Nadia, JangKeun Kim, Eliah G. Overbey, Richa Batra, Annalise Schweickart, Laura Patras, Serena Lucotti, et al. “Secretome profiling captures acute changes in oxidative stress, brain homeostasis, and coagulation following short-duration spaceflight.” Nature Communications Biology.

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• Cope, Henry, Jonas Elsborg, Samuel Demharter, J Tyson Mcdonald, Chiara Wernecke, Hari Parthasarathy, Hriday Unadkat, Mira Chatrathi, Jennifer Claudio, Sigrid Reinsch, Sara Zwart, Scott Smith, Martina Heer, Masafumi Muratani, Cem Meydan, Eliah G. Overbey, JangKeun Kim, Jiwoon Park, Jonathan Schisler, Christopher Mason, Nathaniel Szewczyk, Craig Willis, Amr Salam, Afshin Beheshti. “More than a Feeling: Dermatological Changes Impacted by Spaceflight.” Nature Communications Medicine.

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• Borg, Josef, Afshin Beheshti, JangKeun Kim, Namita Damle, Cem Meydan, Masafumi Muratani, Eliah G. Overbey, Krista Ryon, Sara Zwart, Scott Smith, Braden Tierney, Christopher Mason, Joseph Borg. “Spatiotemporal Expression and Control of Haemoglobin in Space.” Nature Communications.

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• Garcia Medina, J. Sebastian, S Narayanan, Karolina Sienkiewicz, Eliah G. Overbey, Kirill Grigorev, Krista Ryon, Jacqueline Proszynski, et al. “Stability Contrasts with Immune, cfDNA, mitochondrial, and telomere length changes to Short Duration Spaceflight.” Precision Clinical Medicine.

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• Caicedo, Andrés, Verónica Castañeda, Juan Díaz, Alissen Haro-Vinueza, Jiwoon Park, JangKeun Kim Kim, Eliah G. Overbey, et al. “Key Genes, Altered Pathways and Potential Treatments for Muscle Loss in Astronauts and Sarcopenic Patients.” Nature Communications.

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• Andrea Camera, Marshall Tabetah, Verónica Castañeda, JangKeun Kim, Aman Singh, Alissen Haro-Vinueza, Ivonne Salinas, Allen Seylani, Shehbeel Arif, Saswati Das, Marcelo Mori, Anthony Carano, Lorraine Christine De Oliveira, Masafumi Muratani, Richard Barker, Victoria Zaksas, Chirag Goel, Eleni Dimokidis, Deanne Taylor, Jisu Jeong, Eliah G. Overbey, et al. “Aging and putative frailty biomarkers are altered by spaceflight.” Scientific Reports.

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• Beheshti, Afshin, Vera Paar, Siyi Jiang, Angela Enriquez, JangKeun Kim, Henver Brunetta, Masafumi Muratani, Angela Kubik, Noah Allen, Elizabeth Blaber, Eliah G. Overbey, et al. “Countermeasures for cardiac fibrosis in space travel: It takes more than a towel for a hitchhiker's guide to the galaxy”. NPJ Microgravity.

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• J Tyson McDonald, Lily Farmerie, Meghan Johnson, Jiwoon Park, JangKeun Kim, Eliah G. Overbey, Jeffrey Haltom, et al. “So Long, and Thanks for All the Antagomirs: Space Radiation Damage Rescued by Inhibition of Key Spaceflight Associated miRNAs”. Nature Communications.

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• Begum Aydogan Mathyk, Marshall Tabetah, Rashid Karim, Victoria Zaksas, JangKeun Kim, I Anu, Masafumi Muratani, Alexia Tasoula, Ruth Singh, Yen-Kai Chen, Eliah G. Overbey, et al. “Spaceflight alters insulin and estrogen signaling pathways”. Nature Communications.

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In Press

• Overbey, Eliah G., Krista Ryon, JangKeun Kim, Braden Tierney, Remi Klotz, Veronica Ortiz, Sean Mullane, et al. “Collection of Biospecimens from the Inspiration4 Mission Establishes the Standards for the Space Omics and Medical Atlas (SOMA).” Nature Communications.

 

• Park, Jiwoon, Eliah G. Overbey, S. Anand Narayanan, JangKeun Kim, Braden T Tierney, Namita Damle, Deena Najjar, et al. “Spatial multi-omics of human skin reveals KRAS and inflammatory responses to spaceflight.” Nature Communications.

 

• Braden T. Tierney, JangKeun Kim, Eliah G. Overbey, Krista A. Ryon, Jonathan Foox, Maria Sierra, Chandrima Bhattacharya, et al. “Viral activation and ecological restructuring characterize a microbiome axis of spaceflight-associated immune activation.” Nature Microbiology.

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Published

• Overbey, Eliah G., Saswati Das, Henry Cope, Pedro Madrigal, Zaneta Andrusivova, Solène Frapard, Rebecca Klotz, et al. “Challenges and Considerations for Single-Cell and Spatially Resolved Transcriptomics Sample Collection during Spaceflight.” Cell Reports Methods 2, no. 11 (November 2022): 100325. https://doi.org/10.1016/j.crmeth.2022.100325.

 

• Cahill, Thomas, Henry Cope, Joseph J. Bass, Eliah G. Overbey, Rachel Gilbert, Willian Abraham Da Silveira, Amber M. Paul, et al. “Mammalian and Invertebrate Models as Complementary Tools for Gaining Mechanistic Insight on Muscle Responses to Spaceflight.” International Journal of Molecular Sciences 22, no. 17 (August 31, 2021): 9470. https://doi.org/10.3390/ijms22179470.

 

• Overbey, Eliah G., Theros T Ng, Pietro Catini, Lisa M Griggs, Paul Stewart, Suzana Tkalcic, R David Hawkins, Yvonne Drechsler. “Transcriptomes of an Array of chicken ovary, intestinal, and immune cells and tissues.” Frontiers in Genetics, 12. https://doi.org/10.3389/fgene.2021.664424

 

• Overbey, Eliah G., Amanda M. Saravia-Butler, Zhe Zhang, Komal S. Rathi, Homer Fogle, Willian A. Da Silveira, Richard J. Barker, et al. “NASA GeneLab RNA-Seq Consensus Pipeline: Standardized Processing of Short-Read RNA-Seq Data.” iScience 24, no. 4 (April 2021): 102361. https://doi.org/10.1016/j.isci.2021.102361.

 

• Overbey, Eliah G., Willian Abraham Da Silveira, Seta Stanbouly, Nina C. Nishiyama, Gina D. Roque-Torres, Michael J. Pecaut, David Carl Zawieja, et al. “Spaceflight Influences Gene Expression, Photoreceptor Integrity, and Oxidative Stress-Related Damage in the Murine Retina.” Scientific Reports 9, no. 1 (September 16, 2019): 13304. https://doi.org/10.1038/s41598-019-49453-x.

 

• Overbey, Eliah G., Amber M. Paul, Willian A. Da Silveira, Candice G.T. Tahimic, Sigrid S. Reinsch, Nathaniel Szewczyk, Seta Stanbouly, Charles Wang, Jonathan M. Galazka, and Xiao Wen Mao. “Mice Exposed to Combined Chronic Low-Dose Irradiation and Modeled Microgravity Develop Long-Term Neurological Sequelae.” International Journal of Molecular Sciences 20, no. 17 (August 22, 2019): 4094. https://doi.org/10.3390/ijms20174094.

 

• Battle, Stephanie L., Naresh Doni Jayavelu, Robert N. Azad, Jennifer Hesson, Faria N. Ahmed, Eliah G. Overbey, Joseph A. Zoller, et al. “Enhancer Chromatin and 3D Genome Architecture Changes from Naive to Primed Human Embryonic Stem Cell States.” Stem Cell Reports 12, no. 5 (May 2019): 1129–44. https://doi.org/10.1016/j.stemcr.2019.04.004.

 

• Cacchiarelli, Davide, Xiaojie Qiu, Sanjay Srivatsan, Anna Manfredi, Michael Ziller, Eliah G. Overbey, Antonio Grimaldi, et al. “Aligning Single-Cell Developmental and Reprogramming Trajectories Identifies Molecular Determinants of Myogenic Reprogramming Outcome.” Cell Systems 7, no. 3 (September 2018): 258-268.e3. https://doi.org/10.1016/j.cels.2018.07.006.